Shuqing He


2009-2014 Joint PhD, University of Chinese Academy of Sciences & Max Planck Institute for Polymer Research
2005-2009 Bachelor, Wuhan University of Technology


Work experience
2019-now Research Assistant Professor, Southern University of Science and Technology
2017-2019 Visiting Scholar, Molecular Imaging Program of Stanford, Stanford University
2017-2019 Postdoctoral Fellow, Shenzhen University
2015-2017 Postdoctoral Fellow, Singapore University of Technology and Design


Research Interests
Nanomedicine, Molecular imaging probes, Photo-switchable polymer, NIR-II imaging, Multimodal imaging


2019 Shenzhen Overseas High-level Talents-B
2012-2014 Chinese Academy of Sciences & Max Planck Society Scholarship
2012-2013 National Scholarship
2012-2013 Excellent students of the Chinese Academy of Sciences
2011-2012 SGL Group Scholarship


(1) Shuqing He, #Si Chen, # Junle Qu, Zhen Cheng, et al. A high affinity to skeleton rare earth doped nanoparticles for near-infrared II imaging, Nano Letters, 2019, (IF: 12.08, Accept, #contributed Equal)
(2) Shuqing He, Junle Qu and Zhen Cheng, et al. Enhancing photoacoustic intensity of upconversion nanoparticles by photoswitchable azobenzene-containing polymers for dual NIR-II and photoacoustic imaging in vivo, Advanced Optical Materials, 2019, (IF: 7.43, Accept)
(3) Shuqing He, Jun Song, Junle Qu and Zhen Cheng, Crucial breakthrough of second near-infrared biological window fluorophores: design and synthesis toward multimodal imaging and theranostics, Chemical Society Reviews, 2018, 47: 4258-4278. (IF: 40.18)
(4) Zhijun Chen#, Shuqing He#, Si Wu, Hans-Jürgen Butt, Photon Upconversion Lithography: Patterning of Biomaterials Using Near-Infrared Light, Advanced Materials, 2015, 27(13): 2203-2206. (IF: 21.95, #contributed equally)
(5) Shuqing He, Kristina Krippes, Hans-Jürgen Butt, et al. Ultralow-intensity near-infrared light induces drug delivery by upconverting nanoparticles, Chemical Communication, 2015, 51(2): 431- 434. (IF: 6.29)
(6) Shuqing He, Shouchun Zhang, Chunxiang Lu. Facile and Efficient Route to Polyimide-TiO2 Nanocomposite Coating onto Carbon Fiber, ACS Applied Materials & Interfaces. 2011, 3: 4744-4750. (IF: 8.10)
(7) Xinyu Zhao#, Shuqing He# and Mei Chee Tan, Advancements in infrared imaging platforms: complementary imaging systems and contrast agents, Journal of Materials Chemistry B, 2017, 5, 4266-4275. (IF: 4.78, #contributed equally)
(8) Zhenghuan Zhao#, Harini Kantamneni#, Shuqing He#, Vidya Ganapathy, and Mei Chee Tan, et al. Surface-Modified Shortwave-Infrared-Emitting Nanophotonic Reporters for Gene-Therapy Applications, ACS Biomaterials Science & Engineering, 2018, 4 (7): 2350-2363 (IF: 4.43, #contributed equally)
(9) Shuqing He, Xinyu Zhao and Mei Chee Tan, Synthesis of uniform rare earth doped Gd2O2S sub-micron sized spheres using gas-aided sulfurization and their optical characteristics RSC Advances, 2017, 7, 35738-35751. (IF: 2.93)
(10) Xinyu Zhao, Shuqing He and Mei Chee Tan. Design of infrared-emitting rare earth doped nanoparticles and nanostructured composites, Journal of Materials Chemistry C, 2016, 4, 8349-8372. (IF: 5.98)

Zhiyong Guo

Research Interests:
1. Time-resolved fluorescence imaging devices R & D for pathological diagnostics
2. Industrialization of super resolution fluorescence imaging system
2011-2015, Ph. D. in Control Theory and Control Engineering, China University of Petroleum (Beijing)
2008-2011, M.S in Precision Instrument and Machinery, Southwest Petroleum University
2004-2008, B.S in Communication Engineering, Yangtze University
Work Experience:
2019-present, Research Assistant Professor, Department of Biomedical Engineering, Southern University of Science and Technology, China
2015-2018, Lecturer/Master Supervisor, School of Mechanical Engineering, Southwest Petroleum University, China
2016-2017, Visiting Scholar, University of Technology Sydney, Australia
Funding Projects:
Director, Magnetic Anomaly Based Monitoring and Locating of Pig for Large Oil and Gas Pipeline, Applied Basic Research Project of Sichuan Provincial Science and Technology Department (General Programs), 2017-2019
Principal Investigator, ARC Research Hub for Integrated Device for End-user Analysis at Low-levels (IDEAL Hub), Australia, 2016
Principal Investigator, Research on New Method of Underground Pipeline Detection Based on Joint Inversion of Three-layer Magnetic Anomaly Components, Natural Science Foundation of China, 2014-2017
Honors and Awards:
Sichuan Province Overseas High-level Talents, 2018
Selected Publications:
[1] Xu W., Guo Z. Y.*, Wu P., Chen W. H., Characteristic of magnetic fluctuation of underground passing pig with magnets label. Journal of sensor. 2019, 2374246.
[2] Xu W., Guo Z. Y.*, Liu Z. X., Zhang P., Zhou Y. X., Wu P., Detection optimization of single-axis magnetic anomaly sensor for pig clog locating in low latitude area. Petroleum. 2019, 5(1).
[3] Xu X. X., Zhou Z. G., Liu Y. T., Wen S. H., Guo Z. Y., Gao L. X., Wang F.*, Optimising passivation shell thickness of single upconversion nanoparticles using a time-resolved spectrometer. APL Photonics, 2019, 4(2): 026104.
[4] Wang D.J., Di X. J., Wang B. M., Wang F., Guo Z. Y., Jin D. Y.*, Advance in single nanoparticle tracking in living cells [J]. Chinese Optics, 2018, 11(3), 281-295.
[5] Guo Z. Y., Liu D. J.*, Pan Q., Zhang Y. Y., Li Y., Wang Z., Vertical magnetic field and its analytic signal applicability in oilfield underground pipeline detection [J]. Journal of Geophysics and Engineering, 2015, 12(3): 340-350.
[6] Guo Z. Y., Liu D. J.*, Pan Q., Zhang Y. Y., Forward modeling of total magnetic anomaly over a pseudo-2D underground ferromagnetic pipeline [J]. Journal of Applied Geophysics, 2015, 113: 14-30.
Authorized patents:
[1] Guo Z. Y., Chen Z., Liang H. B., et al., A Method of Monitoring and Locating of Pig for Large Oil and Gas Pipeline, Invention Patent, No. ZL 201610885029.1.
[2] Guo Z. Y., Zhang H., Liang H. B., et al., A Method of Magnetization Field Based Detecting and Locating for underground ferrous pipeline, Invention Patent, No. ZL 201610993338.0.
[3] Guo Z. Y., Liu X. P., Du J., et al., Buried Depth Optimization Inversion Based on Magnetic Dipole Reconstruction for Underground Ferrous Pipeline, Invention Patent, No. ZL 2016112149 08.8.
[4] Guo Z. Y., Ren W., Liu L., et al., A Multifunctional Fluorescent Sample Luminescence Tester, Utility Patent, No. ZL 201721284178.9.
[5] Guo Z. Y., Xu W., Liu D., et al., An Automatic Dish Recognition Device Based on Magnetic Sensor Array. Utility Patent, No. ZL 201821034099.7.
[6] Xu W., Guo Z. Y., Wu P., et al., An Adjustable Lens Mounting Seat. Utility Patent, No. ZL 201710943778.X.
[7] Xu W., Guo Z. Y., Liu D., et al., A Lens Mounting Seat with Multiple Degrees of Freedom Adjustable. Utility Patent, No. ZL 201711201800.X.
[8] Xu W., Guo Z. Y., Wu P., et al., A Rotary Unplugging Pig. Utility Patent, No. ZL 201721013 881.6.

Chao Liu

Chao Liu is an Assistant Professor at Southern University of Science and Technology (2019-present). Chao received his Bachelor of Applied Science in Engineering Science from University of Toronto (2008), in Canada. He received his Master of Applied Science in Mechanical Engineering (2010) and PhD in Biomedical Engineering at the Institute of Biomaterials and Biomedical Engineering, University of Toronto (2016). Chao has completed a postdoctoral fellowship at New York University with joint appointment from the Department of Biomedical Engineering and Department of Orthopedics at NYU Langone Health medical center. Chao’s research interests include the mechanobiology of bone cells and stem cells, and tissue engineering of bone tissue for regenerative medicine applications of enhancing bone repair.


2010-2016 PhD, Institute of Biomaterials & Biomedical Engineering (IBBME), University of Toronto, Canada
2008-2010 MASc, Mechanical Engineering, University of Toronto, Canada
2003-2008 BASc, Engineering Science – Biomedical Engineering, University of Toronto, Canada


Work Experience:
2019-present, Assistant Professor, Department of Biomedical Engineering, Southern University of Science and Technology
2016-2019, Post-doctoral Fellow, Department of Biomedical Engineering, Langone Medical Center, New York University


Honors and Awards:
2017 International Federation of Musculoskeletal Research Societies Travel Grant
2016 American Society of Bone and Mineral Research Young Investigator Travel Grant
2010-2014 Canadian Institutes of Health Research Travel Awards
2011-2013 Ontario Graduate Scholarship
2008, 2010 Barbara and Frank Milligan Graduate Fellowship


Research Interests:
Stem cell tissue engineering using mechanical forces and scaffolds in the musculoskeletal system.
(1) Utilize mechanical forces to alter bone forming (osteogenic) and blood vessel forming (angiogenic) stem cells that ultimately enhance bone regeneration
(2) Develop implants with functional macro- and micro-geometry to enhance the activity of angiogenic and osteogenic stem cells
(3) Develop 3D real-time cellular and molecular imaging modalities to observe the bone repair process in situ.


Selected Publications:

1. Chao Liu, Pamela Cabahug‐Zuckerman, Christopher Stubbs, Martin Pendola, Cinyee Cai, Kenneth A. Mann, and Alesha B. Castillo. “Mechanical loading promotes the expansion of primitive osteoprogenitors and organizes matrix and vascular morphology in long bone defects.” Journal of Bone and Mineral Research (2019).
2. Ma, Yu-Heng Vivian; Lam, Candy; Dalmia, Shreyash ; Gao, Peter; Young, Jacob; Middleton, Kevin; Liu, Chao; You, Lidan. “Mechanical regulation of breast cancer bone metastasis via direct and indirect osteocyte signalling in vitro” Journal of Cellular Biochemistry. 2018, Accepted.
3. Chao Liu, Robert Carrera, Vittoria Flamini, Lena Kenny, Pamela Cabahug-Zuckerman, Benson George, Daniel Hunter, Bo Liu, Gurpreet Singh, Philipp Leucht, Kenneth A Mann, Jill A Helms, Alesha B Castillo, “Effects of mechanical loading on cortical defect repair using a novel mechanobiological model of bone healing” Bone. 2018, 108, pp. 145-155.
4. Qian, Weiyi; Gong, Lanqi; Cui, Xin; Zhang, Zijing; Bajpai, Apratim; Liu, Chao; Castillo, Alesha; Teo, Jeremy; Chen, Weiqiang “Nanotopographic regulation of human mesenchymal stem cell osteogenesis” ACS Applied Materials & Interfaces. 2017, 9 (48), pp 41794–41806.
5. Bradaschia-Correa V, Josephson AM, Mehta D, Mizrahi M, Neibart SS, Liu C, Kennedy OD, Castillo AB, Egol KA, Leucht P. “The selective serotonin re-uptake inhibitor fluoxetine directly inhibits osteoblast differentiation and mineralization during fracture healing in mice.” Journal of Bone and Mineral Research. 32(4) 2017: 821–833.
6. Chao Liu, Xin Cui, Thomas Michael Ackermann, Vittoria Flamini, Weiqiang Chen, Alesha Castillo “Osteoblast-Derived Paracrine Factors Regulate Angiogenesis in Response to Mechanical Stimulation” Integrative Biology 8(7) 2016, 785-794.
7. Chao Liu, Xiaoqing Zhang, Michael Wu, Lidan You “Mechanical Regulation of Osteocyte Responses to Physical Damage in vitro” Journal of Biomechanics 2015. 48(16): 4221-4228.
8. Ashutosh Parajuli*, Chao Liu*, Wen Li*, Xiaoyu Gu, Xiaohan Lai, Christopher Price, Lidan You, X. Lucas Lu, Liyun Wang “Bone’s Responses to Mechanical Loading are Impaired in Type 1 Diabetes” Bone 81 (2015) 152–160. (*Equal contributions).
9. Jia-Ning Zhang, Yan Zhao, Chao Liu, Elizabeth S. Han, Xue Yu, Darcy Lidington, Steffen-Sebastian Bolz, Lidan You “The Role of the Sphingosine-1-Phosphate Signaling Pathway in Osteocyte Mechanotransduction Bone” Bone 79 (2015) 71-78. 
10. Chao Wei, Beiyuan Fan, Deyong Chen, Chao Liu, Yuanchen Wei, Bo Huo, Lidan You, Junbo Wang and Jian Chen “Osteocyte Culture in Microfluidic Devices” Biomicrofluidics. 9, 014109 (2015).
11. Wing-Yee Cheung, Chao Liu, Craig A. Simmons, Lidan You, “Osteocyte Apoptosis is Mechanically Regulated and Induces Angiogenesis In Vitro”, Journal of Orthopedic Research, 2011 April ;29(4):523-30.
12. Chao Liu, Yan Zhao, Wing-Yee Cheung, Ronak Gandhi, Liyun Wang, Lidan You “Effects of cyclic hydraulic pressure on osteocytes” Bone. 46 (5), May 2010, pp. 1449-1456.
13. Chao Liu, Alesha B. Castillo, “Targeting Osteogenesis-Angiogenesis Coupling for Bone Repair” Journal of the American Academy of Orthopaedic Surgeons. 2018 (invited review).
14. Jan-Hung Chen*, Chao Liu*, Lidan You, Craig A. Simmons, “Boning up on Wolff’s Law: Mechanical regulation of the cells that make and maintain bone” Journal of Biomechanics 43 (1), pp. 108-118 (*Equal contributions) (invited review).

Bin Tang


PhD, Mechanical Engineering, The University of Hong Kong,HongKong, P.R. China,2002.1 -2006.1.

B. Engg,Materials Science and Engineering,Tongji University,Shanghai, P.R. China,1997.9 -2001.9

Academic Position

05/2006 – 01/2007 Research Assistant(I), Department of Mechanical Engineering, The University of Hong Kong

02/2006 – 05/2006 Research Assistant(II), Department of Mechanical Engineering, The University of Hong Kong

01/2007 – 05/2007 Research Associate, Department of Mechanical Engineering, The University of Hong Kong

05/2006 – 05/2011 Research Assistant Professor, Department of Mechanical Engineering, The University of Hong Kong.

05/2007- 05/2012 Honorary Assistant Professor , Department of Mechanical Engineering, The University of Hong Kong

07/2011—07/2012 Research Fellow,  Dept. of Mechanical Engineering, King Abdullah University of Science and Technology

07/2012-present    Associate Professor,Dept. of Biomedical Engineering (primary appointment ), Dept. of Materials Science and Engineering(Joint appointment), Southern University of Science and Technology 

Journal publications

1. Ngan,A.H.W. and Tang, B., Viscoelastic effects during unloading in depth-sensing indentation. Journal of Materials Research, 2002. 17(10): p.2604-2610.

2. Tang, B. and A.H.W. Ngan, Accurate measurement of tip-samplecontact size during nanoindentation of viscoelastic materials. Journal of Materials Research, 2003. 18(5):p. 1141-1148. 

3. Tang, B., A.H.W. Ngan, and W.W. Lu, Viscoelastic effects during depth-sensing indentation of cortical bone tissues. Philosophical Magazine, 2006. 86(33-35): p.5653-5666. 

4. Tang, B. and A.H.W. Ngan, Nanoindentation measurement of mechanical properties of soft solid covered by a thin liquid film. Soft Materials, 2007. 5(4): p. 169-181. 

5. Tang, B., A.H.W. Ngan and W.W. Lu, An improved method for the measurement of mechanical properties of bone by nanoindentation. Journal of Materials Science-Materials in Medicine, 2007. 18(9): p. 1875-1881. 

6. Tang, B., A.H.W. Ngan, and J.B. Pethica, A method to quantitatively measure the elastic modulus of materials in nanometer scaleusing atomic force microscopy. Nanotechnology, 2008. 19(49). 

7. Tang, B. and A.H.W. Ngan, Nanoindentation using an atomicforce microscope. Philosophical Magazine, 2011. 91(7-9): p. 1329-1338. 

8. Tang, B., K.E. Aifantis, and A.H.W. Ngan, Elastic modulus of nanostructured polymer surfaces. Materials Letters, 2012. 67(1): p. 237-240. 

9. Tang, B. and A.H.W. Ngan, A rate-jump method for characterization of soft tissues using nanoindentation techniques. Soft Matter,2012. 8(22): p. 5974-5979. 

10. Wen,C.Y., C.B. Wu, B. Tang, T. Wang, C.H. Yan, W.W. Lu, H. Pan, Y. Hu, and K.Y.Chiu, Collagen fibril stiffening in osteoarthritic cartilage of human beings revealed by atomic force microscopy. Osteoarthritis and Cartilage, 2012. 20(8): p. 916-922. (Co- first author) 

11. Zhou,Z.L., Tang, B.*, A.H.W. Ngan, Z.N.Dong, and Y.S. Wu, Hepatitis B surface antigen-antibody interactions studied by optical tweezers. IET Nanobiotechnology, 2012. 6(1): p. 9-15. (corresponding author) 

12. Zhou,Z.L., Tang, B.*, A.H.W. Ngan The biomechanics of drug-treated leukemia cells investigated using optical tweezers. Nano Life, 2012, 2, p1250010-1 to 1250010-10. (corresponding author) 

13. Wu,K.S., Li, S.Y., Lo, A.C.Y., Ngan, A.H.W., Wong, D.S.H., So, K.F., Ellis-Behnke,R.G., Tang, B.*. Micro-scale Stiffness Change of Cornea Tissues Suffered from Elevated Intraocular Pressure Investigated by Nanoindentation. Soft Materials, 2013, 11: p 244-253.(corresponding author) 

14. Zhou, Z.L., Cheng,C.X., Li, S., Zhou, X.F., Liu, Z.H., He, Q.T., Zhang, N.N., Ngan, A.H.W., Tang,B.*, Wang, A.X.*. AFM nanoindentation detection of the elastic modulus of tongue squamous carcinoma cells with different metastatic potentials,Nanomedicine: Nanotechnology, Biology and Medicine,publish online,doi:10.1016/j.nano.2013.04.001(corresponding author)